3-Oxazolidinecarboxylic acid, 4-ethynyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R)- - Names and Identifiers
Name | (R)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine
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Synonyms | (R)-N-Boc-2,2-dimethyl-4-ethynyloxazolidine (R)-2,2-DIMETHYL-3-BOC-4-ETHYNYLOXAZOLIDINE (R)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine (4R)-3-(tert-Butoxycarbonyl)-4-ethynyl-2,2-dimethyloxazolidine (R)-tert-Butyl 4-ethynyl-2,2-dimethyloxazolidine-3-carboxylate (4R)-4-Ethynyl-2,2-dimethyl-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester 3-Oxazolidinecarboxylic acid, 4-ethynyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R)-
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CAS | 162107-48-4
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3-Oxazolidinecarboxylic acid, 4-ethynyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R)- - Physico-chemical Properties
Molecular Formula | C12H19NO3
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Molar Mass | 225.28 |
Density | 1.06 |
Boling Point | 277℃ |
Flash Point | 121℃ |
pKa | -3.39±0.60(Predicted) |
Storage Condition | 2-8°C |
3-Oxazolidinecarboxylic acid, 4-ethynyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R)- - Introduction
(R)-2,2-dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine, also known as tert-butoxycarbonylethynyloxazolidine, is an organic compound. Its chemical formula is C12H18N2O2, and its relative molecular mass is 226.28g/mol.
properties:(R)-2,2-dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine is a colorless to pale yellow oily liquid. It has a lower melting and boiling point. This compound is soluble in solvents and stable in air.
Uses: This compound is commonly used as a catalyst in organic synthesis. It can be used in asymmetric synthesis reactions such as asymmetric coupling reactions and asymmetric reduction reactions. In addition, it can also be used as a precursor for ligands and catalysts to participate in metal-catalyzed reactions.
preparation method:(R)-2,2-dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine preparation method is more complex, usually requires a multi-step reaction. A common preparation method is to graft 2-ethynyl oxazolidine and CO, and then go through the synthesis and separation purification steps to obtain the desired product.
Safety information: This compound has no obvious safety hazards under normal use conditions, but it is still necessary to comply with laboratory safety procedures. In case of contact with skin or eyes, rinse immediately with plenty of water. Avoid inhaling its vapors or dust and ensure good ventilation.
Last Update:2024-04-10 22:29:15